Alarelin Acetate (GnRH agonist) is a single, non-glycosylated synthetic polypeptide chain containing 9 amino acids and has a molecular mass of 1167.3 Dalton.
Alarelin is a synthetic polypeptide which acts as LH-RH (Luteinizing-hormone releasing hormone) analogue agonist. LH-RH is secreted in the hypothalamus and its release induces the secretion of LH (luteinizing hormone) and FSH (Follicle-stimulating hormone) from the pituitary gland. These two hormones act on the ovaries and the testes and are responsible of the profertility effects of LHRH through the release of steroidal hormones.
The biological activity of Alarelin, a synthetic LH-RH agonist, is dozens of times higher than that of LH-RH in the test of rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro and in the ovulation induction test.
Gonadotropin-releasing hormone (GnRH) superagonist, luteinizing hormone-releasing hormone agonist, luteinising hormone-releasing hormone agonist, GnRH agonist, LHRH agonist
C56H78N16O12 x C2H4O2
Amino Acid Sequence
5-oxo-pro-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Nhet x CH3COOH.
CAS REGISTRY NO.
Greater than 99.0%.
Sterile-filtered white lyophilized (freeze-dried) powder. The Alarelin peptide was lyophilized with no additives.
It is recommended to reconstitute the lyophilized Alarelin in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Shipped at ambient temperature. Upon receipt, store at the temperature recommended below.
This product is intended for Laboratory Research Use Only. Not for use in diagnostic or therapeutic procedures. This product may not be used as a pharmaceutical or veterinary drug, agricultural product, or food additive.