Collection: Metatissue® Human Protein-Based Biomaterials

Human-based products for Cell Culture and Tissue Engineering

Metatissue® is focused on designing and manufacturing human protein-based products that find application in cell culture, tissue engineering and regeneration and disease modelling.

Metatissue® biomaterials provide realistic microenvironments for cell culture allowing for greater cell-to-cell and cell-to-matrix interaction resemblance, thereby increasing the accuracy of in vitro studies.

The extracellular matrix of living tissues is composed by a great diversity of structural proteins and bioactive factors. For this reason, mimicking its function in vitro continues to be a big challenge. Metatissue® uses ethically sourced human proteins to produce the next-generation of xeno-free biomimetic 3D cell culture platforms.

Applications

• 3D cell culture: Cell growth and expansion.
• Tissue engineering: Platform that supports tissue regeneration.
• Disease modeling: Drug discovery and screening.
• Cancer research: Tumor-like microenvironments.
• Stem cell research: Suitable for stem cell proliferation.
• Microtissue development: Tissue morphogenesis and homeostatis.

Advantages

• Human-derived: Multiple native human-derived proteins and growth factors provide a xeno-free alternative to animal products.
• Mechanically tuneable: Mechanical properties can be easily adjusted to obtain several tissue stiffness simulations.
• Photocrosslinkable: The precursor solution can be cured upon light exposure to induce hydrogel crosslinking. Its temperature stability allows for easier handling.
  
• Versatile: Easily processed in multiple geometries and in microarrays amenable to organ-on-a-chip systems designed for high throughput screening applications.
• Reproducible: The materials are prepared from multiple donor units that are pooled to minimize lot-to-lot variation.
• Personalized: Under request, specific products may be prepared with samples from a specific donor, enriched or depleted in specific target molecules.

Ilex Life Sciences LLC is an authorized worldwide distributor of Metatissue® products.