Ossiform P3D Scaffolds Support Normal Morphology of Osteoblasts

Ossiform P3D Scaffolds, consisting of 3D-printed β-tricalcium phosphate (β-TCP), are a unique, polymer-free, natural bone model.

The latest research from Ossiform has shown that the P3D Scaffolds have great osteogenic properties and that osteoblasts maintain their genotype and morphological phenotype. After culturing osteoblasts for 2-5 weeks, the results are clear.

Ossiform P3D Scaffolds support normal morphology of osteoblasts

​Osteoblastic marker genes are upregulated in response to traditional cell culturing. Confocal imaging shows how the P3D scaffolds allow the osteoblasts to organize in a 3D oriented manner, surrounded by their collagen-rich extracellular matrix. 

Studying the osteoblasts and their extracellular matrix closer using scanning electron microscopy, you can really appreciate how the osteoblasts are retaining their round morphology, and how the extracellular matrix is spanning widely across the scaffold clearly indicative of the first steps in bone formation.

To learn more about Ossiform's P3D Scaffolds, please visit the pages below:

Acknowledgement: This content has been adapted from Ossiform ApS. Ilex Life Sciences is an authorized distributor of Ossiform P3D Scaffolds.