Description
Gelacell™ is a unique, 3D microfibrous scaffold specifically engineered for advanced in vitro 3D cell culture and tissue engineering applications. Designed as a non-woven, highly porous scaffold, Gelacell™ offers exceptional biocompatibility and non-toxicity across a variety of cell types.
Gelacell™ nanofibrous scaffolds are available in a variety of materials and formats.
This product is a 10 cm × 10 cm scaffold sheet made from pharmaceutical grade polycaprolactone + poly lactic-co-glycolic acid (PCL:PLGA) that offers a 3D structure allowing cells to grow in a more physiologically relevant manner, promoting cell-cell interactions, tissue-like organization, and cell polarization, which are challenging to achieve in traditional 2D cell culture. The sheet can be used in its presented format or can be cut into desired shape and sizes depending on the user's experimental needs and setups. The scaffold is tailored for the cultivation of complex systems like cell microenvironments, tissue regeneration, and organoids, Gelacell™ also makes a robust platform for drug screening and other cell culture investigations. The optimized design of the scaffold ensures thermal, chemical, and mechanical stability, while also providing substantial swelling capabilities and porosity, allowing efficient nutrient diffusion and thereby preventing cellular waste build up.
Features
- 3D architecture with a substantial available surface area.
- Minimal modifications required for transitioning from 2D to 3D culture.
- Stable mechanical properties.
- 10 cm × 10 cm scaffold can be cut into desired shape and sizes.
- Flexibility of scaffolds facilitates easy handleability.
- Porous structure promotes cell migration and efficient diffusion of nutrients, solutes, and gases.
- Compatibility with a variety of cell lines and culture conditions.
- Polymeric scaffolds: biocompatibility, diversity, and widely accepted in cellular applications.
- Sterilized by Gamma irradiation and remains sterile until the pack is opened.
- Storage at room temperature.
Specifications
| Catalog No. |
GC0801RN-SC-C |
| Polymer/Material |
Polycaprolactone + Poly (lactic-co-glycolic acid). PCL:PLGA is 70:30, both polymers are pharmaceutical grade. |
| Format | 10x10 cm sheet (ideal for tissue engineering/organoid scaffolds) |
| Appearance (dry) | White |
| Appearance (swelled in water/PBS) | White (translucent) |
| Fiber Orientation | Random |
| Fiber Diameter | ≅ 0.90 μm |
| Thickness | 0.165 ± 0.006 mm |
| Area Density | ≅ 5.6 g/m^2 |
| Porosity | ≅ 88% |
| Wettability | Hydrophilic |
| Absorptivity in PBS (pH 7.4 at 37°C) | ≅ 1300% (The material was kept soaked for 24 hours in PBS at 37°C) |
| Degradation (in PBS at 37°C) | Negligible |
| pH (of PBS solution after 24 hours) | 7.4 – 7.5, without observable changes |
| % Elongation | 29.8% ± 1.2% |
| Modulus | 1940 kPa ± 200 kPa |
| Ultimate stress | 250 kPa ± 21 kPa |
| Manufacturer | Gelatex Technologies |
| Country of Origin | Estonia |
Storage & Stability
Sterility and performance properties are maintained when stored at room temperature, with a shelf life of two years from the date of manufacture.
Resources
Related Products
Ilex Life Sciences LLC is an authorized distributor of Gelatex Technologies' Gelacell™ products.