Description
Gelacell™ is a unique, 3D microfibrous scaffold specifically engineered for advanced in vitro 3D cell culture and tissue engineering applications. Designed as a non-woven, highly porous scaffold, Gelacell™ offers exceptional biocompatibility and non-toxicity across a variety of cell types.
Gelacell™ nanofibrous scaffolds are available in a variety of materials and formats.
This variant of Gelacell™ is specially designed for medium-to-long term cell culture durations. Scaffolds made from pharmaceutical grade poly-L-lactide (PLLA) are fixed to cell crowns in a 12-well plate. The cell crowns act as Boyden chambers for facilitating studies related to air-liquid interface culture, co-culture, complex tissue models, etc. Gelacell™ also makes a robust platform for drug screening and other cell culture investigations. The optimized design of the scaffold ensures thermal, chemical, and mechanical stability, while also providing substantial swelling capabilities and porosity, allowing efficient nutrient diffusion and thereby preventing cellular waste build up.
Features
- 3D architecture with a substantial available surface area.
- 12 well plate with cell crowns.
- Minimal modifications required for transitioning from 2D to 3D culture.
- Stable mechanical properties.
- Scaffold fixed in a cell crown acting as Boyden chamber for complex culture.
- Flexibility of scaffolds facilitates easy handleability.
- Porous structure promotes cell migration and efficient diffusion of nutrients, solutes, and gases.
- Compatibility with a variety of cell lines and culture conditions.
- Polymeric scaffolds: biocompatibility, diversity, and widely accepted in cellular applications.
- Sterilized by Gamma irradiation and remains sterile until the pack is opened.
- Storage at room temperature.
Specifications
| Catalog No. |
GC0805RN-CC12-B |
| Polymer/Material |
Poly-L-lactide (PLLA), also known as Poly-L-lactic acid, pharmaceutical grade |
| Format |
Scaffolds on cell crowns in plates (ideal for long term 3D cell culture):
|
| Appearance (dry) | White |
| Appearance (swelled in water/PBS) | White (translucent) |
| Fiber Orientation | Random |
| Fiber Diameter | 2.0 μm - 2.6 μm |
| Thickness | 137 μm - 200 μm |
| Area Density | 4 g/m^2 - 5 g/m^2 |
| Porosity | ≅ 90% |
| Wettability | Hydrophilic |
| Absorptivity in PBS (pH 7.4 at 37°C) | 806% ± 66% (The material was kept soaked for 24 hours in PBS at 37°C) |
| Degradation (in PBS at 37°C) | Neglible |
| pH (of PBS solution after 24 hours) | 7.4 – 7.5, without observable changes |
| % Elongation | 25% ± 2.78% |
| Modulus | 1046 kPa ± 157 kPa |
| Ultimate stress | 190 kPa ± 22 kPa |
| Manufacturer | Gelatex Technologies |
| Country of Origin | Estonia |
Storage & Stability
Sterility and performance properties are maintained when stored at room temperature, with a shelf life of two years from the date of manufacture.
Resources
Related Products
Ilex Life Sciences LLC is an authorized distributor of Gelatex Technologies' Gelacell™ products.