PAN-Biotech Stable Glutamine 200 mM (100x), L-alanyl-L-glutamine dipeptide, 50 ml bottle, cell culture media supplement, cat. no. P04-82050, distributed by Ilex Life Sciences.
PAN-Biotech Stable Glutamine 200 mM (100x), L-alanyl-L-glutamine dipeptide, 100 ml bottle, cell culture media supplement, cat. no. P04-82100, distributed by Ilex Life Sciences.
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PAN-Biotech Stable Glutamine 200 mM (100x)

P04-82050
$39.00
$39.00
$46.00
Unavailable
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Introduction

Stable Glutamine 200 mM solution contains L-alanyl-L-glutamine dipeptide, an alternative to L-Glutamine, which is an essential amino acid required by all mammalian cells but is more unstable in cell culture solutions than other amino acids. The rate and extent of L-Glutamine degradation are related to storage temperature, age of the product and pH. Stable Glutamine has an increased stability that improves cell health. It is suitable for both adherent and suspension culture of mammalian cells with no adaptation needed.

Advantages

  • Minimizes toxic ammonia build-up: Stable glutamine does not spontaneously break down to form ammonia. Instead, cells cleave the dipeptide bond to release L-Glutamine as needed.
  • Improves cell viability and growth: cultures with lower levels of ammonia show improved cell viability.
  • Remains stable across a wide range of temperatures.

Application

Stable Glutamine 200 mM contains 200 mM L-alanyl-L-glutamine dipeptide in 0.85% NaCl. 10 ml of stable glutamine solution is sufficient for up to one liter of medium.

Composition

L-Alanyl-L-Glutamine 43,440.00 mg/L 
Sodium Chloride 8,500.00 mg/L

Specifications

Cat. No. P04-82050, P04-82100

Concentration: 100x concentrated
Liquid / Powder: Liquid
Product Category: Amino acids & vitamins
Product Type: Stable Glutamine (L-alanyl-L-glutamine dipeptide)
Size: Various
Sterile: Yes
Storage Temperature: +2°C - +8°C
Manufacturer: PAN-Biotech GmbH
Country of Origin: Germany

    Documents

    Product References

    • Schmidt, Sara C et al. “Microscopic clusters feature the composition of biochemical tetraspanin-assemblies and constitute building-blocks of tetraspanin enriched domains.” Scientific reports vol. 14,1 2093. 24 Jan. 2024, doi:10.1038/s41598-024-52615-1
    • Karaca, Mawien et al. “Adverse outcome pathway-based analysis of liver steatosis in vitro using human liver cell lines.” STAR protocols vol. 4,3 (2023): 102500. doi:10.1016/j.xpro.2023.102500
    • Wollschlaeger, Jannis O et al. “Scaffolds for Cultured Meat on the Basis of Polysaccharide Hydrogels Enriched with Plant-Based Proteins.” Gels (Basel, Switzerland) vol. 8,2 94. 4 Feb. 2022, doi:10.3390/gels8020094
    • Reppert, Nikolas, and Thorsten Lang. “A conserved sequence in the small intracellular loop of tetraspanins forms an M-shaped inter-helix turn.” Scientific reports vol. 12,1 4494. 16 Mar. 2022, doi:10.1038/s41598-022-07243-y
    • Godoy, Patricio et al. “Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.” Archives of toxicology vol. 87,8 (2013): 1315-530. doi:10.1007/s00204-013-1078-5

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    Ilex Life Sciences LLC is an authorized distributor of PAN-Biotech products.