Description
LAP (Lithium phenyl-2,4,6-trimethylbenzoylphosphinate) is a widely used photoinitiator in photocrosslinking reactions, enabling the crosslinking of water-soluble macromolecules with photoreactive groups into hydrogels or bioinks under light exposure.
LAP efficiently crosslinks upon exposure to visible light at approximately 405 nm. LAP is generally cytocompatible, with recommended concentrations for cell culture experiments ranging from 0.05% to 1%, depending on the photocrosslinkable material, to maintain compatibility. Usually, polymerization kinetics using LAP enable cell encapsulation with lower initiator concentrations and longer wavelength light, improving cell viability and reducing initiator toxicity. Nevertheless, higher LAP concentrations may pose cytotoxic and mutagenic risks to cells. LAP concentration may also influence the mechanical properties of the crosslinked material.
LAP is the recommended photoinitiator for Metatissue® hPLMA - Human Methacryloyl Platelet Lysates Photopolymerizable Hydrogel.
Features
- High water solubility.
- Cytocompatible.
- Sensitive to visible light.
- The solution can be sterilized with a 0.22 µm sterile filter.
Specifications
| CAS Registry No.: | 85073-19-4 |
| Molecular Formula: | C16H16LiO3P |
| Molecular Weight: | 294.21 g/mol |
| Product Category: | Hydrogels, scaffolds, biomatrices |
|
Product Type: |
Hydrogel accessory |
| Liquid/Powder: | Lyophilized powder |
| Appearance: | White to off-white powder or filaments |
| Size: | 500 mg |
| Purity: | ≥ 95% |
| Storage: | 2-8°C, protected from light and moisture. |
| Manufacturer: | Metatissue® |
| Country of Origin: | Portugal |
Documents
Usage
This product is intended for Laboratory Research Use Only. Not for use in diagnostic or therapeutic procedures. This product may not be used as a pharmaceutical or veterinary drug, agricultural product, or food additive.
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Ilex Life Sciences LLC is an authorized worldwide distributor of Metatissue® products.