Introduction
PAN-Biotech Amphotericin B (250 µg/ml) is a generic version of Fungizone that is used in cell culture applications. Amphotericin B is an antifungal agent produced by Streptomyces sp.. Amphotericin B increases fungal plasma membrane permeability by binding to sterols, thereby protecting cell cultures from contamination by yeast and multicellular fungi.
Application
Amphotericin B is often used as an antifungal, anti-yeast and anti-mold agent to prevent fungal contamination of cell cultures. The commonly recommended working concentration ranges from 0.25-2.5 μg/mL (1-10 mL/L).
Composition
| Components | Concentration |
| Amphotericin B |
250.00 mg/L |
| Sodium deoxycholate | 195.00 mg/L |
| NaH2PO4 x H2O |
127.70 mg/L |
Specifications
| Liquid / Powder: | liquid |
|---|---|
| Product Category: | Antibiotics and Antifungal Drugs |
| Product Type: | Amphotericin B |
| Size: | various |
| Sterile: | Yes |
| Storage Temperature: | -20°C |
| Manufacturer | PAN-Biotech GmbH |
| Country of Origin | Germany |
Usage
This product is intended for Laboratory Research Use Only. Not for use in diagnostic or therapeutic procedures. This product may not be used as a pharmaceutical or veterinary drug, agricultural product, or food additive.
Documents
Product References
- Mayr, Hermann O et al. “Effect of Vancomycin, Gentamicin and Clindamycin on Cartilage Cells In Vitro.” Biomedicines vol. 11,12 3143. 25 Nov. 2023, doi:10.3390/biomedicines11123143
- Johansen, Bianca et al. “First Evidence of a Combination of Terpinen-4-ol and α-Terpineol as a Promising Tool against ESKAPE Pathogens.” Molecules (Basel, Switzerland) vol. 27,21 7472. 2 Nov. 2022, doi:10.3390/molecules27217472
- Miescher, Iris et al. “Impact of High-Molecular-Weight Hyaluronic Acid on Gene Expression in Rabbit Achilles Tenocytes In Vitro.” International journal of molecular sciences vol. 23,14 7926. 18 Jul. 2022, doi:10.3390/ijms23147926
- Sbirkov, Yordan et al. “A Colorectal Cancer 3D Bioprinting Workflow as a Platform for Disease Modeling and Chemotherapeutic Screening.” Frontiers in bioengineering and biotechnology vol. 9 755563. 18 Nov. 2021, doi:10.3389/fbioe.2021.755563
- Johansen, Bianca et al. “Antimicrobial Spectrum of Titroleane™: A New Potent Anti-Infective Agent.” Antibiotics (Basel, Switzerland) vol. 9,7 391. 8 Jul. 2020, doi:10.3390/antibiotics9070391
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