Introduction
PAN-Biotech Penicillin-Streptomycin solution contains 10,000 U/ml Penicillin and 10 mg/ml Streptomycin.
The antibiotics penicillin and streptomycin are used to prevent bacterial contamination of cell cultures to due their effective combined action against gram-positive and gram-negative bacteria. Penicillin was originally purified from the fungus Penicillium and acts by interfering directly with the turnover of the bacterial cell wall and indirectly by triggering the release of enzymes that further alter the cell wall. Streptomycin was originally purified from Streptomyces griseus. It acts by binding to the 30S subunit of the bacterial ribosome, leading to inhibition of protein synthesis and death in susceptible bacteria.
Application
Penicillin-Streptomycin is used to supplement cell culture media to control bacterial contamination. It is recommended for use in cell culture applications at 10 µL/ml.
Composition
| Components | Concentration |
| Streptomycin sulfate | 10,000.00 mg/L |
| Sodium chloride | 8,500.00 mg/L |
| Penicillin G potassium salt | 10,000,000.00 Units/L |
Specifications
| Liquid / Powder: | liquid |
|---|---|
| Product Category: | Antibiotics and Antifungal Drugs |
| Product Type: | Penicillin-Streptomycin |
| Size: | various |
| Sterile: | Yes |
| Storage Temperature: | -20°C |
| Manufacturer | PAN-Biotech GmbH |
| Country of Origin | Germany |
Usage
This product is intended for Laboratory Research Use Only. Not for use in diagnostic or therapeutic procedures. This product may not be used as a pharmaceutical or veterinary drug, agricultural product, or food additive.
Documents
Product References
- Chiriac, Ştefania et al. “New 3D Printed Scaffolds Based on Walstromite Synthesized by Sol-Gel Method.” Journal of functional biomaterials vol. 15,1 19. 8 Jan. 2024, doi:10.3390/jfb15010019
- Schmidt, Sara C et al. “Microscopic clusters feature the composition of biochemical tetraspanin-assemblies and constitute building-blocks of tetraspanin enriched domains.” Scientific reports vol. 14,1 2093. 24 Jan. 2024, doi:10.1038/s41598-024-52615-1
- Döring, Marietta et al. “Nucleolar protein TAAP1/C22orf46 confers pro-survival signaling in non-small cell lung cancer.” Life science alliance vol. 7,4 e202302257. 16 Jan. 2024, doi:10.26508/lsa.202302257
- Skovronova, Renata et al. “Adipose stromal cells bioproducts as cell-free therapies: manufacturing and therapeutic dose determine in vitro functionality.” Journal of translational medicine vol. 21,1 723. 16 Oct. 2023, doi:10.1186/s12967-023-04602-9
- Haghshenas, Babak et al. “Cytotoxic effect of potential probiotic Lactiplantibacillus plantarum KUMS-Y8 isolated from traditional dairy samples on the KB and OSCC human cancer cell lines.” Heliyon vol. 9,9 e20147. 15 Sep. 2023, doi:10.1016/j.heliyon.2023.e20147
- Handwerk, Leonie et al. “Simulating Space Conditions Evokes Different DNA Damage Responses in Immature and Mature Cells of the Human Hematopoietic System.” International journal of molecular sciences vol. 24,18 13761. 6 Sep. 2023, doi:10.3390/ijms241813761
- Sporbeck, Katharina et al. “The ABL-MYC axis controls WIPI1-enhanced autophagy in lifespan extension.” Communications biology vol. 6,1 872. 24 Aug. 2023, doi:10.1038/s42003-023-05236-9
- Liu, Heng et al. “Structural insights into anion selectivity and activation mechanism of LRRC8 volume-regulated anion channels.” Cell reports vol. 42,8 (2023): 112926. doi:10.1016/j.celrep.2023.112926
- Qi, Chao et al. “Structure of the connexin-43 gap junction channel in a putative closed state.” eLife vol. 12 RP87616. 3 Aug. 2023, doi:10.7554/eLife.87616
- Pucelik, Barbara et al. “DYRK1A inhibitors leucettines and TGF-β inhibitor additively stimulate insulin production in beta cells, organoids, and isolated mouse islets.” PloS one vol. 18,5 e0285208. 17 May. 2023, doi:10.1371/journal.pone.0285208
- Calcat-I-Cervera, Sandra et al. “Harmonised culture procedures minimise but do not eliminate mesenchymal stromal cell donor and tissue variability in a decentralised multicentre manufacturing approach.” Stem cell research & therapy vol. 14,1 120. 4 May. 2023, doi:10.1186/s13287-023-03352-1
- Hartmann, Julia et al. “Molecular and Functional Characterization of Different BrainSphere Models for Use in Neurotoxicity Testing on Microelectrode Arrays.” Cells vol. 12,9 1270. 27 Apr. 2023, doi:10.3390/cells12091270
- And many more on PubMed Central!
Related Products
Ilex Life Sciences LLC is an authorized distributor of PAN-Biotech products.