Introduction
CMRL 1066 Medium is a chemically-defined medium, which was developed in the late 1950s by Connaught Medical Research Laboratories. CMRL 1066 was originally designed for serum-free culture of L-strain cells, as a highly modified and less complex version of Medium 199 (M199). It has been used to maintain monolayer growth of permanent cell lines for years without protein supplementation. Initially developed for serum-free conditions, it can be supplemented with serum and used to support the growth of many types of cells.
GMP Grade
CMRL-1066 GMP is a ready-to-use, chemically-defined cell culture medium designed for direct use in GMP-regulated clinical and industrial applications. It provides a precisely controlled formulation that supports stable and reproducible cell culture performance.
The GMP grade version is based on the established CMRL-1066 formulation originally developed by Connaught Medical Research Laboratories and is manufactured under strictly controlled GMP conditions. Combined with high batch-to-batch consistency, controlled quality parameters and comprehensive documentation, CMRL-1066 GMP is a true ready-to-use medium suitable for sensitive development, scale-up and manufacturing workflows.
Applications
- Cultivation of immortalized cell lines under GMP conditions.
- Clinical cell processing and cell therapy.
- Cell and gene therapy workflows.
- Biopharmaceutical development and manufacturing.
- Serum-free or chemically defined cell culture systems.
Features
- Manufactured in compliance with Good Manufacturing Practice (GMP).
- Chemically defined formulation.
- Ready-to-use – immediately applicable.
- High batch-to-batch consistency and process reliability.
Composition
CMRL-1066 is a nucleoside-rich and vitamin-rich medium. This version of CMRL-1066 contains no L-Glutamine and no Phenol Red, and is buffered with 2.2 g/L NaHCO3. CMRL-1066 contains no proteins, lipids, or growth factors.
Specifications
Cat. No. CT-84600
| Quality: | GMP Grade (EU Annex 1) |
|---|---|
| Bicarbonate: | With 2.2 g/L Sodium Bicarbonate |
| Glucose: | With glucose |
| Glutamine: | No Glutamine |
| HEPES: | Without HEPES |
| Liquid / Powder: | Liquid |
| Phenol Red: | Without Phenol Red |
| Product Category: | Cell Culture Media |
| Product Type: | CMRL 1066 |
| Size: | 500 ml bottles |
| Sodium Pyruvate: | Without Sodium Pyruvate |
| Sterile: | Yes |
| Storage Temperature: | +2°C - +8°C |
| Manufacturer: | PAN-Biotech GmbH |
| Country of Origin: | Germany |
Related Products
- PAN-Biotech GMP Grade Cell Culture Products
- RUO Version: PAN-Biotech CMRL 1066, w/o: L-Glutamine, w/o: Phenol red, w: 2.2 g/L NaHCO3
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