Pregnant Mare Serum Gonadotropin (PMSG)
Pregnant Mare Serum Gonadotropin (PMSG), also known as Equine Chorionic Gonadotropin (eCG), is a complex 43–63 kda glycoprotein purified from the serum of pregnant mares. Our bioactive PMSG hormone is lyophilized with no additives.
Our PMSG and Human Chorionic Gonadotropin (hCG) products are often used in protocols for superovulation in laboratory animals. Superovulation, also known as controlled ovarian hyperstimulation, is a process where exogenous gonadotropic hormones are administered to cause a synchronized release of a larger than normal amount of oocytes. PMSG is more likely to be used than other pituitary hormones due to having a longer circulatory half-life.
Superovulation methods are commonly used in the production of genetically modified laboratory animals, such as genetically engineered mouse models (GEMM) by pronuclear microinjection (transgenic mouse), targeted mutations through CRISPR-Cas9 methods, and embryonic stem (ES) cell-based gene targeting to produce "knockout" mice. PMSG + hCG are also used in superovulation of Sprague-Dawley and Wistar rats. PMSG and hCG may be used with a variety of other species; for example, they are often used in the generation of Xenopus laevis and Xenopus tropicalis eggs or embryos for use in experimental model systems.
To learn more about our PMSG, please visit the product page: