NEW PRODUCT: beadMATRIX+: precoated microcarriers for iPSCs culture!
We are happy to announce the availability of a new product from denovoMATRIX!
beadMATRIX+ are animal component-free, pre-coated microcarriers specifically designed for bioreactor-scale expansion of iPSCs in serum-free and xeno-free media. The coating formulation is based on the successful 2D coating product myMATRIX iPSC and tailored to support customers in the establishment of translational cell therapies. Documentation describing quality and origin characteristics are provided.
The composition of the beadMATRIX coating has has been further improved to optimally support the expansion of iPSC. iPSCs cultured with beadMATRIX+ proliferate fast and reliable over 3 passages (21 days) while remaining pluripotent and genetically stable. High expression of the stemness genes OCT4, SOX2, SSEA-4, and TRA-1-60 is ensured over multiple passages in a 3D culture setup. The results show that beadMATRIX+ supports dynamic culture of iPSCs and can be implemented for efficient iPSC manufacturing for clinical applications.