Introduction
PAN-Biotech Penicillin-Streptomycin Solution contains 10,000 U/ml Penicillin and 10 mg/ml Streptomycin.
The antibiotics penicillin and streptomycin are used to prevent bacterial contamination of cell cultures to due their effective combined action against gram-positive and gram-negative bacteria. Penicillin was originally purified from the fungus Penicillium and acts by interfering directly with the turnover of the bacterial cell wall and indirectly by triggering the release of enzymes that further alter the cell wall. Streptomycin was originally purified from Streptomyces griseus. It acts by binding to the 30S subunit of the bacterial ribosome, leading to inhibition of protein synthesis and death in susceptible bacteria.
GMP Grade
Penicillin–Streptomycin Solution GMP Grade is a ready-to-use antibiotic solution designed for direct use in GMP-regulated clinical and industrial applications.
The GMP grade version is based on the proven penicillin–streptomycin formulation and is manufactured under strictly controlled GMP conditions. Defined quality parameters, high batch-to-batch consistency and comprehensive documentation make Penicillin–Streptomycin GMP a true ready-to-use solution, suitable for immediate implementation in sensitive cell culture and manufacturing workflows.
Application
Penicillin-Streptomycin, also known as Pen-Strep, is used to supplement cell culture media to control bacterial contamination. It is recommended for use in cell culture applications at 10 µL/ml.
- Supplementation of cell culture media under GMP conditions.
- Control of bacterial contamination.
- Clinical cell processing and cell therapy.
- Cell and gene therapy workflows.
- Biopharmaceutical development and manufacturing.
Features
- Manufactured in compliance with Good Manufacturing Practice (GMP).
- Ready-to-use – immediately applicable.
- High batch-to-batch consistency and process reliability.
Composition
| Components | Concentration |
| Streptomycin sulfate: | 10,000.00 mg/L |
| Sodium chloride: | 8,500.00 mg/L |
| Penicillin G potassium salt: | 10,000,000.00 Units/L |
Specifications
Cat. No.: CT-07110
| Quality: | GMP Grade (EU Annex 1) |
|---|---|
| Liquid / Powder: | Liquid |
| Product Category: | Antibiotics and Antifungal Drugs |
| Product Type: | Penicillin-Streptomycin |
| Size: | 100 ml bottles |
| Sterile: | Yes |
| Storage Temperature: | -20°C |
| Manufacturer: | PAN-Biotech GmbH |
| Country of Origin: | Germany |
Related Products
- RUO Version: PAN-Biotech Penicillin-Streptomycin Solution (10,000 U/ml Penicillin, 10 mg/ml Streptomycin)
- PAN-Biotech GMP Grade Cell Culture Products
- PAN-Biotech L-Glutamine–Penicillin–Streptomycin
- PAN-Biotech Penicillin-Streptomycin-Amphotericin B Mix
- PAN-Biotech Amphotericin B (Fungizone), 250 µg/ml
- PAN-Biotech Gentamicin Sulfate Solution, 10 mg/ml
- Antibiotics and Antifungal Drugs
Ilex Life Sciences LLC is an authorized distributor of PAN-Biotech products.