NEW Application Note: Growth factor stabilization by myMATRIX coatings

denovoMATRIX has published a new Application Note in which they describe the effect of myMATRIX coatings on growth factors.

denovoMATRIX myMATRIX technology triples lifetime of FGF2 growth factor

Growth factors are part of the cellular microenvironment and are stabilized by the cell surrounding extracellular matrix (ECM) components such as glycosaminoglycans (GAGs). myMATRIX ECM-mimetic coatings, which contain GAGs, tripled the half-life of the growth factor basic fibroblast growth factor (FGF2) in comparison to other cell culture coatings. This stabilization supported the maintenance of stemness and promoted the survival of neural precursor cells (NPCs), especially when applying restricted feeding regimes.

These results show that myMATRIX coatings improve growth factor stability and allow for reduced growth factor replenishment which reduces costs and simplifies stem cell culture.

You can read the full application note here: Growth factor stabilization by myMATRIX coatings


This content has been adapted from denovoMATRIX.

Ilex Life Sciences is an authorized distributor of myMATRIX products manufactured by denovoMATRIX.