3-D Life Hydrogels User Applications

3-D Life Biomimetic Hydrogels for 3D Cell Culture

Want to know if your cell lines or primary cells have been used with 3-D Life Hydrogels?

3-D Life Hydrogels, manufactured by Cellendes GmbH and distributed by Ilex Life Sciences, have been referenced in scientific literature for use in a wide variety of applications with many different cell lines and primary cells:

Cell lines	Application	Reference/Publication
A375 (melanoma, human) SKMEL28 (melanoma, human) MNT1 (melanoma, human) SKMEL23 (melanoma, human) Me290 (melanoma, human)	Cell migration assay	Militaru, Ioana V et al. (2023)
U937 (lymphoblast) HL-60 (promyelocytic) HaCaT (keratinocyte) MFC-7 (mamma carcinoma, human) H838 (lung carcinoma)	Tumor-stroma model	Hensler et al. (2021)
MFC-7 (mamma carcinoma, human) 3T3 (fibroblasts, murine)	Tumor-stroma model	Charwat et al. (2015) Wang et al. (2019) Application Note 3 (AN 3)
HT29 (colon adenocarcinoma, human) MDCK (kidney epithelial, canine)	Epithelial barrier model Microfluidics	Nair et al. (2021)
OCI-AML3 (leukemic)	Migration assay	Zippel et al. (2019)
HepG2 (hepatocyte carcinoma, human)	Spheroid culture	Miyakawa et al. (2018)
HepG2 (hepatocyte carcinoma, human) Huh-7 (hepatocyte carcinoma, human)	Mechanotransduction	Shen et al. (2019)
MCF10A (mammary breast epithelial, non tumorigenic, human)	Cancer research	Grobe et al. (2018) Grikscheit et al. (2015)
U87 (glioblastoma, human)	Cancer research, chemotaxis Cell migration	Huang et al. (2018)
MDCK (kidney epithelial, canine)	Epithelial cyst formation	Application Note 1 (AN 1)
HKC-8 (kidney proximal tubular, human) PU009-F (renal fibroblasts, human)	Kidney fibrosis model	Nugraha et al. (2017)
KCOT (keratocystic odontogenic tumor, human)	Cancer research Spheroid culture	Noguchi et al. (2017)
3T3 (fibroblast, murine)	Tisssue engineering	Koenig et al. (2016)
HCT-116 (colon carcinoma, human)	Drug screening	Rimann et al. (2014)
HeLa (adenocarcinoma, human) HT1080 (epithelial cancer cell line from fibrosarcoma, human) MDA-MB-231 (mamma carcinoma, human NES (neuroepithelial-like stem cell derived from H9 hESC, human)	Microarray	Ueda et al. (2012)
C2C12 (myoblasts, murine)	Cell-matrix interactions Mechanotransduction	Wang et al. (2021) Yin et al. (2021)

Primary cells	Application	Reference/Publication
Fibroblasts (human)	Tumor-stroma model	Hensler et al. (2021)
hMSCs (human mesenchymal stem cells)	Mechanotransduction	Wang et al. (2021) Benz et al. (2010)
Chondrocytes	Tissue engineering Cell-based therapeutic development	Lang et al (2021) Rothdiener et al. (2018) Benz et al. (2010)
Pancreatic progenitor cells (human)	Organoid culture	Georgakopoulos et al. (2020)
Cardiomyocytes (murine)	Mechanotransduction	Friedrich et al. (2019) Friedrich et al. (2017)
PBMCs (human peripheral blood mononuclear cells)	Lymph node model Perfusion	Kraus et al. (2019)
APCs (antigen presenting cells) DCs (dentritic cells) ATSVF (Adipose tissue stromal vascular fraction) BM-MSC (bone marrow mesenchymal stem cells) ADSCs (adipose-derived stem cells) UC-MSC (umbilical cord mesenchymal stem cells)	Human artificial lymph node (HuALN) model	Sardi et al. (2016)
EPCs (endothelial progenitor cells, murine)	Matrix-stiffness-dependent cell differentiation Hydrogel implantation in mice	Xue et al. (2019)
Neurospheres (human)	Neurotoxicity testing	Hellwig et al. (2018)
Nucleus pulposus (human)	Mechanotransduction	He et al. (2018)
Intervertebral disk cells (human)	Cell-based therapeutic development	Benz et al. (2010)
Pancreatic islets (murine) AT-MSCs (adipose tissue derived mesenchymal stem cells, murine)	Cell-based therapeutic development; implantation	Ayenehdeh et al. (2017)
HUVECs (Human Umbilical Vein Endothelial Cells)	Cell-based therapeutic development; implantation Angiogenesis	Koenig et al. (2016) Sun et al. (2014)

To learn more, please visit the 3-D Life Biomimetic Hydrogels page.

The content on this page has been adapted from Cellendes GmbH. Ilex Life Sciences LLC is an official distributor of Cellendes 3-D Life Hydrogel products.