Description
Apo Lactoferrin Human Recombinant, expressed in rice, lyophilized powder is a glycosylated mature polypeptide sequence with a molecular mass of approximately 80 kDa. The apo lactoferrin protein is purified by proprietary chromatographic techniques.
Summary
Lactoferrin is a glycoprotein that belongs to the transferrin family of iron binding proteins. It is found in human breast milk as well as most epithelial surface secretions including tears, nasogastric, saliva, and bronchial. Lactoferrin binds two molecules of iron with very high affinity. Lactoferrin inhibits bacterial growth by withholding iron; its N-terminal region is an antimicrobial peptide. Lactotransferrin acts synergistically with lysozyme to potentiate the activity of both proteins.
The multifunctional protein lactoferrin has many physiological possible roles. It is often referred to as an innate defense protein and frequently serves as the first line of defense in protection against pathogens. It has been shown to have the ability to bind iron, it is a natural anti-bacterial, anti-fungal and anti-viral, it is an antioxidant and it also has immunomodulatory properties. It has many beneficial properties, which make it a good candidate for a number of cell culture and research applications.
Apo vs Holo Lactoferrin
- Apo-lactoferrin: Refers to lactoferrin that is not bound to iron, or has very low iron saturation (less than 5%).
- Holo-lactoferrin: Refers to lactoferrin that is saturated with iron.
Specifications
| Product Category: |
Media supplements |
| Product Type: |
Protein |
| Source: |
Expressed in Rice Grain plant (Oryza sativa) |
| Appearance: |
Pink lyophilized powder. |
| Formulation: | The protein was lyophilized with no additives. |
| Purity (SDS-PAGE): |
> 95% |
| Reconstitution: | It is recommended to reconstitute the lyophilized protein in sterile water at 10 mg/ml, which can then be further diluted to other aqueous solutions. |
| Shipping Condition: | Shipped at ambient temperature. Upon receipt, store the product at the temperature recommended below. |
| Storage Temperature: | Recombinant Apo Lactoferrin, although stable at room temperature for 3 weeks, should be stored 2-8°C. |
Usage
This product is intended for laboratory research use only. Not for use in diagnostic or therapeutic procedures. This product may not be used as a pharmaceutical or veterinary drug, agricultural product, or food additive.
Documents
Other Names
Recombinant Apo-Lactoferrin, Apolactoferrin, Apo LTF, Apo Lactotransferrin, Growth-inhibiting protein 12, Talalactoferrin, iron-depleted lactoferrin