Promed Bioscience Atelocollagen Ultrapure, Porcine Type I, Enzymatic Extraction, Dialyzed, Lyophilized Vial
Promed Bioscience purified atelocollagen characteristics
Promed Bioscience Atelocollagen Ultrapure process
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Atelocollagen Ultrapure, Porcine Type I, Enzymatic Extraction, Dialyzed, Lyophilized

PRO-2003-10
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$235.00
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$235.00
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$279.00
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Description

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Lyophilized Atelocollagen Ultrapure (Cat. No. PRO-2003) is characterized by rich and ultra dialysis-purified Type I collagen content in a regular fibril-like configuration that retains its superior functionality and structural properties. PRO-2003 is extracted from porcine tendon tissue sourced from strictly controlled herds, complying with all EU regulations. The proprietary pepsin enzyme-based extraction removes telopeptides at the nonhelical N and C termini, resulting in a triple helix configuration that exhibits reduced immunogenicity.

Applications

Extracted and dialyzed Atelocollagen Ultrapure is biocompatible and biodegradable and thus suitable for a wide range of research applications. PRO-2003 is ideal for:

  • Bioink for 3D bioprinting
  • In vitro cell cultures
  • Cell functional assays
  • In vitro/in vivo research applications:
    • wound healing
    • tissue regeneration
    • drug delivery
    Figure shows highly purified atelocollagen product, both in lyophilized form (A) and in solution (B), without the presence of other protein impurities or extraction by-products.

    Figure 1. Molecular weight distribution by SDS-PAGE: Figure shows highly purified atelocollagen product, both in lyophilized form (A) and in solution (B), without the presence of other protein impurities or extraction by-products.

    Specifications

    Manufacturer Promed Bioscience Ltd.
    CAS Registry No. 9007-34-5
    Collagen Purity
    > 97% (by SDS/Western blotting)
    Appearance White/Off-white lyophilizate
    Source
    Porcine tendon
    Country of Animal Origin
    Cyprus
    BSE Risk None
    Amino Acid Analysis Typical/characteristic profile
    Electrophoretic Pattern Characteristic pattern, visible α, β, γ bands
    Sterility/Microbiological testing Pass (0 cfu/g)
    Heavy Metals Analysis < 1 ppm
    Sterilization Method Produced under strict aseptic conditions
    Cell Attachment Assay Pass
    Cell Toxicity Assay Pass

    Reconstitution

    • PRO-2003 may be reconstituted to a concentration of 0.5 - 2.0 mg/ml when used as a coating agent and as chemoattractant.
    • For the production of collagen gels, a concentration of 3.0 mg/ml may be used (slow gelation assays - cells will sink to the bottom of the gel).
    • To reconstitute, add 0.1M acetic acid or 0.01M HCl to the vial and let it stand without stirring. Warming to 25˚C may be necessary for lyophilized atelocollagen to dissolve completely (clear solution).

    Storage/Expiration

    Product ships at ambient temperature. Upon receipt, store the product at the temperature recommended below:

    • Long term: storage of lyophilized product at -20°C is recommended, with a storage life of 24 months from the date of manufacturing.
    • Short term: storage of reconstituted product at 2-8°C is recommended, for up to 6 months from the date of reconstitution.

    Usage

    This product is intended for Laboratory Research Use Only. Not for use in diagnostic or therapeutic procedures. This product may not be used as a pharmaceutical or veterinary drug, agricultural product, cosmetic, supplement, or food additive.

    Other Names

    Type 1 Collagen, Type I Collagen, Collagen-1

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    Ilex Life Sciences LLC is an authorized distributor of Promed Biosciences Ltd products.