Description
Deslorelin is a synthetic nonapeptide analogue of the natural gonadotropin releasing hormone (GnRH) with potential antineoplastic activity. Deslorelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Deslorelin has a molecular weight of 1281.64 Dalton.
Summary
Deslorelin is being studied in the treatment of cancer as a way to block sex hormones made by the ovaries or testicles. It belongs to the family of molecules known as gonadotropin-releasing hormone analogs. It is used for the induction of ovulation in mares. Deslorelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors.
Molecular Formula
C64H83N17O12
Amino Acid Sequence
pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHC2H5
CAS REGISTRY NO.
57773-65-6
Other names
Gonadotropin-releasing hormone (GnRH) superagonist, luteinizing hormone-releasing hormone agonist, luteinising hormone-releasing hormone agonist, GnRH agonist, LHRH agonist
Type
Synthetic peptide
Purity
Greater than 99.0%.
Formulation
Sterile-filtered white lyophilized (freeze-dried) powder. The Deslorelin peptide was lyophilized with no additives.
Reconstitution
It is recommended to reconstitute the lyophilized Deslorelin in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Shipping
Shipped at ambient temperature. Upon receipt, store at the temperature recommended below.
Storage/Expiration
Usage
This product is intended for Laboratory Research Use Only. Not for use in diagnostic or therapeutic procedures. This product may not be used as a pharmaceutical or veterinary drug, agricultural product, or food additive.