Follicle Stimulating Hormone (FSH) Human, Native Protein, 5000 IU vial
Follicle Stimulating Hormone (FSH) Human, Native Protein, vial
  • Load image into Gallery viewer, Follicle Stimulating Hormone (FSH) Human, Native Protein, 5000 IU vial
  • Load image into Gallery viewer, Follicle Stimulating Hormone (FSH) Human, Native Protein, vial

Follicle Stimulating Hormone (FSH) Human, Native Protein

A22490100
Regular price
$145.00
Sale price
$145.00
Regular price
$173.00
Temporarily out of stock
Unit price
per 
Shipping calculated at checkout.

Description

FSH Human is a glycoprotein produced from urine of post-menopausal women and has a total molecular mass of 30,000 Dalton. FSH is a heterodimeric hormone consisting of 92 amino acids a chain and 111 amino acids b chain.
The FSH is purified by proprietary chromatographic techniques.

Summary

Follicle stimulating hormone (FSH) is a hormone synthesised and secreted by gonadotropes in the anterior pituitary gland. FSH and luteinizing hormone (LH) act synergistically in reproduction: In women, in the ovary FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows it releases inhibin, which shuts off the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testes and is critical for spermatogenesis. In both males and females, FSH stimulates the maturation of germ cells. In females, FSH initiates follicular growth, specifically affecting granulosa cells. With the concomitant rise in inhibin B FSH levels then decline in the late follicular phase. This seems to be critical in selecting only the most advanced follicle to proceed to ovulation. At the end of the luteal phase, there is a slight rise in FSH that seems to be of importance to start the next ovulatory cycle. Like its partner, LH, FSH release at the pituitary gland is controlled by pulses of gonadotropin-releasing hormone (GnRH). Those pulses, in turn, are subject to the estrogen feed-back from the gonads.

Type

Native Protein

Source

Urine of post-menopausal women.

Formulation

Sterile Filtered White lyophilized (freeze-dried) powder. The FSH was lyophilized with no additives.

Reconstitution

It is recommended to reconstitute the lyophilized Follicle Stimulating Hormone in sterile pyrogen free water at 2,000IU/1ml, which can then be further diluted to other aqueous solutions.

Shipping

At ambient temperature.  Upon receipt, store the product at -18ºC

Storage/Expiration

Lyophilized FSH although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FSH-beta should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Contaminants

Less than: 0.1% hCG, 0.5%TSH, 0.5% LH, 0.5%GH and 0.5%Prl.
Free of HbsAg, antibodies to HIV and HCV.

Other Names

Follitropin subunit beta, Follicle-stimulating hormone beta subunit, FSH-beta, FSH-B, Follitropin beta chain, FSH.

Usage

This product is intended to Laboratory Research Use Only.  This product may not be used a drug, agricultural product, food additives.

RESOURCES