PAN-Biotech MCDB 131, w/o: L-Glutamine, w: 1.176 g/L NaHCO3, 500 ml bottle, cell culture media, cat. no. P04-80057, distributed by Ilex Life Sciences.

PAN-Biotech MCDB 131, w/o: L-Glutamine, w: 1.176 g/L NaHCO3

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MCDB 131 is a medium that was originally developed by Knedler and Ham for the cultivation of human microvascular endothelial cells (HMVEC) under reduced serum content. For this purpose it is often supplemented with dialyzed serum, EGF, and hydrocortisone. MCDB 131 Medium is also suitable for other cell types, including human omental microvascular cells, hepatocytes, myocytes, and smooth muscle cells. Additionally, MCDB 131 has been used for definitive endoderm differentiation of human pluripotent stem cells (hPSCs) as well as a basal medium for mesenchymal stem cells (MSCs) differentiation.

MCDB 131 Medium is formulated with several components not found in traditional basal media, such as trace elements, putrescine, adenine, thymidine, and higher levels of some amino acids and vitamins. This formulation allows the medium to be supplemented with very low levels of serum or defined components.


PAN-Biotech MCDB 131, w/o: L-Glutamine, w: 1.176 g/L NaHCO3


Cat. No. P04-80057

Bicarbonate: With 1.176 g/L Sodium Bicarbonate
Endotoxin Content: Endotoxin Content unspecified
Glucose: With glucose
Glutamine: No Glutamine
Liquid / Powder: Liquid
Phenol Red: With Phenol Red
Product Category: Cell Culture Media
Product Type: MCDB 131
Size: Various
Sodium Pyruvate: With Sodium Pyruvate
Sterile: Yes
Storage Temperature: +2°C - +8°C
Manufacturer: PAN-Biotech GmbH
Country of Origin: Germany


    Product References

    • Jalil, Sami et al. “Genetic and functional correction of argininosuccinate lyase deficiency using CRISPR adenine base editors.” American journal of human genetics vol. 111,4 (2024): 714-728. doi:10.1016/j.ajhg.2024.03.004

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