Description
Triptorelin is a synthetic analogue of gonadorelin (GnRH). The only change between GnRH and Triptorelin is the introduction of a residue of D-Triptophane instead of a glycine in position 6. As a result of the substitution of the 6th amino acid residue in the native molecule, the agonistic effect is more pronounced and the plasma half-life prolonged.
Triptorelin controls release of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) and also levels of testosterone and estrogen.
Formula; Sequence
C64H82N18O13; Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2
CAS Registry No.
57773-63-4
Other names
Gonadotropin-releasing hormone (GnRH) superagonist, luteinizing hormone-releasing hormone agonist, luteinising hormone-releasing hormone agonist, GnRH agonist, LHRH agonist.
Type
Synthetic peptide
Purity
Greater than 98.0%.
Formulation
Sterile-filtered white lyophilized (freeze-dried) powder. The peptide (1 mg/ml) was lyophilized with no additives.
Reconstitution
It is recommended to reconstitute the lyophilized Triptorelin in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Shipping
Shipped at ambient temperature. Upon receipt, store at the temperature recommended below.
Storage/Expiration
Lyophilized Triptorelin, although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution, Triptorelin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Usage
This product is intended for Laboratory Research Use Only. Not for use in diagnostic or therapeutic procedures. This product may not be used as a pharmaceutical or veterinary drug, agricultural product, or food additive.