3-D Life CD-Link (200 µl) Hydrogel Component
3-D Life CD-Link (3x 200 µl) Hydrogel Component
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3-D Life CD-Link Hydrogel Component

L60-1
Regular price
$220.00
Sale price
$220.00
Regular price
Temporarily out of stock
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Description

3-D Life CD-Link is a component of the 3-D Life Hydrogel system. The CD-Link molecule consists of a polyethylene glycol-peptide conjugate carrying a thiol at each end. When combined with polymers of the 3-D Life Hydrogel system, thiol groups on CD-Link form stable thioether bonds with the thiol-reactive groups on the polymers, which results in the formation of the hydrogel.

CD-Link can be used with 3-D Life functionalized polymers Mal-PVA, Mal-Dextran, SG-PVA and SG-Dextran.

CD-Link contains a matrix metalloproteinase (MMP)-cleavable peptide sequence (Pro-Leu-Gly-Leu-Trp-Ala), which is cleaved by a broad range of MMPs including MMP1, MMP3, MMP7 and MMP9. It allows cells to locally degrade the polymer network, if they produce the indicated MMPs.

For using this product please consult General Protocols GP-1 "Preparation of 3-D Life Fast Gelling Hydrogels" or GP-2 "Preparation of 3-D Life Slow Gelling Hydrogels" and the 3-D Life Hydrogels User Guide, which may be downloaded below.

Application

3-D Life CD-Link is used together with thiol-reactive polymers of the 3-D Life Hydrogel system to establish 3-D cell cultures.

Quantity

Cat. No. L60-1: When used with polymers of the 3-D Life Hydrogel system up to 2 ml 3-D Life Hydrogel can be generated, depending on the stiffness of the gel.

Cat. No. L60-3: When used with polymers of the 3-D Life Hydrogel system up to 6 ml 3-D Life Hydrogel can be generated, depending on the stiffness of the gel.

Components

Cat. No. L60-1:

Material Quantity Concentration of reactive groups
CD-Link, Lyophilized
200 µl* 20 mmol/L* MSDS
Water 600 µl n.a. MSDS

*Volume after reconstitution of lyophilisate.

*Concentration after reconstitution of lyophilisate.

 

Cat. No. L60-3:

Material Quantity Concentration of reactive groups
CD-Link, Lyophilized 3 x 200 µl* 20 mmol/L* MSDS
Water 600 µl n.a. MSDS

*Volume after reconstitution of lyophilisate. *Concentration after reconstitution of lyophilisate.

Resources

Application Notes

Ilex Life Sciences LLC is an authorized distributor of Cellendes GmbH.