References to PAN-Biotech Panexin Serum Replacements

PAN-Biotech Panexin Serum Replacement Product Citations

PAN-Biotech Panexin Serum Substitutes

Panexin products are fully defined serum replacements developed and manufactured by PAN-Biotech in Germany, and distributed by Ilex Life Sciences. They can be used for the cultivation of adherent and non-adherent cells under serum-free or serum-reduced conditions. Panexin serum substitutes have been referenced in scientific literature. Below you will find some of the scientific papers that reference Panexin products.

For more information, please visit the serum replacement page.

Panexin Basic

  • Palmieri, Fabio et al. “One-Step Soft Agar Enrichment and Isolation of Human Lung Bacteria Inhibiting the Germination of Aspergillus fumigatus Conidia.” Microorganisms vol. 12,10 2025. 7 Oct. 2024, doi:10.3390/microorganisms12102025
  • Trefny, Marcel P et al. “Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy.” Nature communications vol. 14,1 86. 2 Feb. 2023, doi:10.1038/s41467-022-35583-w
  • Blaskovic, Sanja et al. “Di-Tyrosine Crosslinking and NOX4 Expression as Oxidative Pathological Markers in the Lungs of Patients with Idiopathic Pulmonary Fibrosis.” Antioxidants (Basel, Switzerland) vol. 10,11 1833. 18 Nov. 2021, doi:10.3390/antiox10111833
  • Wanes, Dalanda et al. “Proliferation and Differentiation of Intestinal Caco-2 Cells Are Maintained in Culture with Human Platelet Lysate Instead of Fetal Calf Serum.” Cells vol. 10,11 3038. 5 Nov. 2021, doi:10.3390/cells10113038

Panexin CD

  • Kohs, Jessica et al. “Studies on the Virucidal Effects of UV-C of 233 nm and 275 nm Wavelengths.” Viruses vol. 16,12 1904. 11 Dec. 2024, doi:10.3390/v16121904
  • Perez-Diaz, Noelia et al. “Longitudinal characterization of TK6 cells sequentially adapted to animal product-free, chemically defined culture medium: considerations for genotoxicity studies.” Frontiers in toxicology vol. 5 1177586. 4 Jul. 2023, doi:10.3389/ftox.2023.1177586
  • Gehrke, Miranda et al. “Immunogenicity of Novel AAV Capsids for Retinal Gene Therapy.” Cells vol. 11,12 1881. 9 Jun. 2022, doi:10.3390/cells11121881

Panexin NTA

  • Surur, Abdrrahman Shemsu et al. “Fexinidazole optimization: enhancing anti-leishmanial profile, metabolic stability and hERG safety.” RSC medicinal chemistry, vol. 15,11 3837–3852. 30 Aug. 2024, doi:10.1039/d4md00426d
  • Kohler, Robin, and Kurt Engeland. “A-MYB substitutes for B-MYB in activating cell cycle genes and in stimulating proliferation.” Nucleic acids research vol. 52,12 (2024): 6830-6849. doi:10.1093/nar/gkae370
  • Wurm, Konrad W et al. “Carba Analogues of Flupirtine and Retigabine with Improved Oxidation Resistance and Reduced Risk of Quinoid Metabolite Formation.” ChemMedChem vol. 17,16 (2022): e202200262. doi:10.1002/cmdc.202200262
  • Martin, Catherine Ann et al. “Adipose tissue derived stromal cells in a gelatin-based 3D matrix with exclusive ascorbic acid signalling emerged as a novel neural tissue engineering construct: an innovative prototype for soft tissue.” Regenerative biomaterials vol. 9 rbac031. 24 May. 2022, doi:10.1093/rb/rbac031
  • Wurm, Konrad W et al. “Modifications of the Triaminoaryl Metabophore of Flupirtine and Retigabine Aimed at Avoiding Quinone Diimine Formation.” ACS omega vol. 7,9 7989-8012. 25 Feb. 2022, doi:10.1021/acsomega.1c07103
  • Sotolongo Bellón, Junel et al. “Four-color single-molecule imaging with engineered tags resolves the molecular architecture of signaling complexes in the plasma membrane.” Cell reports methods vol. 2,2 100165. 4 Feb. 2022, doi:10.1016/j.crmeth.2022.100165
  • Wanes, Dalanda et al. “Proliferation and Differentiation of Intestinal Caco-2 Cells Are Maintained in Culture with Human Platelet Lysate Instead of Fetal Calf Serum.” Cells vol. 10,11 3038. 5 Nov. 2021, doi:10.3390/cells10113038
  • Kappes, Lucy et al. “Ambrisentan, an endothelin receptor type A-selective antagonist, inhibits cancer cell migration, invasion, and metastasis.” Scientific reports vol. 10,1 15931. 28 Sep. 2020, doi:10.1038/s41598-020-72960-1
  • Ratschker, Teresa et al. “Mitoxantrone-Loaded Nanoparticles for Magnetically Controlled Tumor Therapy-Induction of Tumor Cell Death, Release of Danger Signals and Activation of Immune Cells.” Pharmaceutics vol. 12,10 923. 27 Sep. 2020, doi:10.3390/pharmaceutics12100923
  • Ender, Fanny et al. “Detection and Quantification of Extracellular Vesicles via FACS: Membrane Labeling Matters!.” International journal of molecular sciences vol. 21,1 291. 31 Dec. 2019, doi:10.3390/ijms21010291
  • Hartmann, Jessica et al. “A Library-Based Screening Strategy for the Identification of DARPins as Ligands for Receptor-Targeted AAV and Lentiviral Vectors.” Molecular therapy. Methods & clinical development vol. 10 128-143. 6 Jul. 2018, doi:10.1016/j.omtm.2018.07.001
  • Kuen, Janina et al. “Pancreatic cancer cell/fibroblast co-culture induces M2 like macrophages that influence therapeutic response in a 3D model.” PloS one vol. 12,7 e0182039. 27 Jul. 2017, doi:10.1371/journal.pone.0182039
  • Poller, Johanna M et al. “Selection of potential iron oxide nanoparticles for breast cancer treatment based on in vitro cytotoxicity and cellular uptake.” International journal of nanomedicine vol. 12 3207-3220. 19 Apr. 2017, doi:10.2147/IJN.S132369
  • Harati, Kamran et al. “Tumor-associated fibroblasts promote the proliferation and decrease the doxorubicin sensitivity of liposarcoma cells.” International journal of molecular medicine vol. 37,6 (2016): 1535-41. doi:10.3892/ijmm.2016.2556
  • Puts, Regina et al. “A Focused Low-Intensity Pulsed Ultrasound (FLIPUS) System for Cell Stimulation: Physical and Biological Proof of Principle.” IEEE transactions on ultrasonics, ferroelectrics, and frequency control vol. 63,1 (2016): 91-100. doi:10.1109/TUFFC.2015.2498042
  • Majety, Meher et al. “Fibroblasts Influence Survival and Therapeutic Response in a 3D Co-Culture Model.” PloS one vol. 10,6 e0127948. 8 Jun. 2015, doi:10.1371/journal.pone.0127948
  • Pajtler, Kristian W et al. “Neuroblastoma in dialog with its stroma: NTRK1 is a regulator of cellular cross-talk with Schwann cells.” Oncotarget vol. 5,22 (2014): 11180-92. doi:10.18632/oncotarget.2611
  • R. Puts, T. Ambrosi, A. Kadow-Romacker, K. Raum, K. Ruschke and P. Knaus, "In-vitro stimulation of cells of the musculoskeletal system with focused Low-Intensity Pulsed Ultrasound (FLIPUS): Analyses of cellular activities in response to the optimized acoustic dose," 2014 IEEE International Ultrasonics Symposium, Chicago, IL, USA, 2014, pp. 1630-1633, doi: 10.1109/ULTSYM.2014.0404.
  • Schmidt, Silvia K et al. “Influence of tryptophan contained in 1-Methyl-Tryptophan on antimicrobial and immunoregulatory functions of indoleamine 2,3-dioxygenase.” PloS one vol. 7,9 (2012): e44797. doi:10.1371/journal.pone.0044797

Panexin NTS

Panexin BMM

  • Legroux, Thierry M et al. “Immunomodulation by glucocorticoid-induced leucine zipper in macrophages: enhanced phagocytosis, protection from pyroptosis, and altered mitochondrial function.” Frontiers in immunology vol. 15 1396827. 23 May. 2024, doi:10.3389/fimmu.2024.1396827
  • Duong, Linh Tuan et al. “GvmR - A Novel LysR-Type Transcriptional Regulator Involved in Virulence and Primary and Secondary Metabolism of Burkholderia pseudomallei.” Frontiers in microbiology vol. 9 935. 16 May. 2018, doi:10.3389/fmicb.2018.00935
  • Bartel, Alexander et al. “Caspase-6 mediates resistance against Burkholderia pseudomallei infection and influences the expression of detrimental cytokines.” PloS one vol. 12,7 e0180203. 7 Jul. 2017, doi:10.1371/journal.pone.0180203
  • Hopf, Verena et al. “BPSS1504, a cluster 1 type VI secretion gene, is involved in intracellular survival and virulence of Burkholderia pseudomallei.” Infection and immunity vol. 82,5 (2014): 2006-15. doi:10.1128/IAI.01544-14
  • Bast, Antje et al. “Caspase-1-dependent and -independent cell death pathways in Burkholderia pseudomallei infection of macrophages.” PLoS pathogens vol. 10,3 e1003986. 13 Mar. 2014, doi:10.1371/journal.ppat.1003986
  • Koh, Gavin C K W et al. “Glyburide reduces bacterial dissemination in a mouse model of melioidosis.” PLoS neglected tropical diseases vol. 7,10 e2500. 17 Oct. 2013, doi:10.1371/journal.pntd.0002500
  • Breitbach, Katrin et al. “Distinct roles for nitric oxide in resistant C57BL/6 and susceptible BALB/c mice to control Burkholderia pseudomallei infection.” BMC immunology vol. 12 20. 16 Mar. 2011, doi:10.1186/1471-2172-12-20
  • Breitbach, Katrin et al. “Caspase-1 mediates resistance in murine melioidosis.” Infection and immunity vol. 77,4 (2009): 1589-95. doi:10.1128/IAI.01257-08
  • Traeger, Tobias et al. “Detrimental role of CC chemokine receptor 4 in murine polymicrobial sepsis.” Infection and immunity vol. 76,11 (2008): 5285-93. doi:10.1128/IAI.00310-08

Panexin (misc.)

  • Davies, Emma L et al. “HCMV carriage in the elderly diminishes anti-viral functionality of the adaptive immune response resulting in virus replication at peripheral sites.” Frontiers in immunology vol. 13 1083230. 15 Dec. 2022, doi:10.3389/fimmu.2022.1083230
  • Steidel, Corinna et al. “Biologically Active Tissue Factor-Bearing Larger Ectosome-Like Extracellular Vesicles in Malignant Effusions from Ovarian Cancer Patients: Correlation with Incidence of Thrombosis.” International journal of molecular sciences vol. 22,2 790. 14 Jan. 2021, doi:10.3390/ijms22020790
  • Houldcroft, Charlotte J et al. “Assessing Anti-HCMV Cell Mediated Immune Responses in Transplant Recipients and Healthy Controls Using a Novel Functional Assay.” Frontiers in cellular and infection microbiology vol. 10 275. 26 Jun. 2020, doi:10.3389/fcimb.2020.00275
  • Ender, Fanny et al. “Tissue factor activity on microvesicles from cancer patients.” Journal of cancer research and clinical oncology vol. 146,2 (2020): 467-475. doi:10.1007/s00432-019-03073-0
  • Vicogne, Dorothée et al. “Fetal bovine serum impacts the observed N-glycosylation defects in TMEM165 KO HEK cells.” Journal of inherited metabolic disease vol. 43,2 (2020): 357-366. doi:10.1002/jimd.12161
  • Lugert, Stephan et al. “Cellular effects of paclitaxel-loaded iron oxide nanoparticles on breast cancer using different 2D and 3D cell culture models.” International journal of nanomedicine vol. 14 161-180. 21 Dec. 2018, doi:10.2147/IJN.S187886
  • Friedrich, Juliane et al. “STAT1 deficiency supports PD-1/PD-L1 signaling resulting in dysfunctional TNFα mediated immune responses in a model of NSCLC.” Oncotarget vol. 9,98 37157-37172. 14 Dec. 2018, doi:10.18632/oncotarget.26441
  • Ridder, Kirsten et al. “Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation.” PLoS biology vol. 12,6 e1001874. 3 Jun. 2014, doi:10.1371/journal.pbio.1001874
  • Into, Takeshi et al. “Regulation of MyD88-dependent signaling events by S nitrosylation retards toll-like receptor signal transduction and initiation of acute-phase immune responses.” Molecular and cellular biology vol. 28,4 (2008): 1338-47. doi:10.1128/MCB.01412-07
  • Peter, Jochen F et al. “Enrichment and detection of molecules secreted by tumor cells using magnetic reversed-phase particles and LC-MALDI-TOF-MS.” Journal of biomolecular techniques : JBT vol. 18,5 (2007): 287-97.

... and many more on https://pubmed.ncbi.nlm.nih.gov/ !

Ilex Life Sciences LLC is an authorized distributor of Panexin products, manufactured by PAN-Biotech.