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Panexin NTS Fully-Defined Serum Substitute for Suspension Cells

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PAN-Biotech Panexin NTS is a ready-to-use, fully defined serum substitute for the cultivation of suspension cells under serum-free conditions. Panexin NTS is developed with a unique technology and contains a special 3-dimensional substance release system (3D-SRS) for an optimal support of cells with nutrients and growth stimulants. The sterile solution is added to the culture medium in a final concentration of 10%. It supports the growth of many cell types in an optimum manner.


Panexin NTS contains purified proteins, lipids, salts, amino acids, trace elements, and hormones in an optimized formulation and a new 3-dimensional substance release system (3D-SRS). Panexin NTS contains no growth factors, undefined hydrolysates or peptones. Animal-derived components are < 2% w/v. Customized formulations (e.g. without hormones and insulin) on request.


Panexin NTS can be used for many cell lines to replace FBS. Due to specially selected and pretested raw materials Panexin NTS batches are very homogeneous. Therefore the complex batch testing known from FBS can be omitted with the use of Panexin NTS. Panexin NTS is fully defined and contains no growth factors, undefined peptones or hydrolysates. Due to this special formulation the interpretation of results from studies on effects of individually added growth factors is easier and more reliable in serum-free conditions. For cell lines which require specific growth factors these should be added in a concentration as previously used.


Panexin NTS is suitable for the cultivation of a variety of non-adherent suspension cells under serum-free conditions.

Graph: efficiency and cell growth stimulation of Panexin NTS compared to FBS

Overall performance varies based upon the cell line and the basal media used.

Table: comparison of cell growth in 10% Panexin NTS in different basal media versus cell growth in 10% FBS in different basal media


    Cell Type: Various suspension cells
    Culture Type: Suspension culture
    Liquid / Powder: liquid
    Product Category: Serum Replacements
    Size: Various
    Sterile: Yes
    Storage Temperature: -20°C, in the dark
    Manufacturer PAN-Biotech GmbH
    Country of Origin Germany


    This product is intended for Laboratory Research Use Only. Not for use in diagnostic or therapeutic procedures. This product may not be used as a pharmaceutical or veterinary drug, agricultural product, or food additive.

    Other Names

    FBS replacement, FBS substitute, serum substitute


      Product References

      • Frost, Joe N et al. “Plasma iron controls neutrophil production and function.” Science advances vol. 8,40 (2022): eabq5384. doi:10.1126/sciadv.abq5384
      • Mahboudi, Fereidoun et al. “The Role of Different Supplements in Expression Level of Monoclonal Antibody against Human CD20.” Avicenna journal of medical biotechnology vol. 5,3 (2013): 140-7.

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